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George Kittle and Nick Bosa Set for 49ers Return in NFL Season Opener

San Francisco 49ers stars George Kittle and Nick Bosa are cleared to play in tonight’s NFL Week 1 international matchup against the Los Angeles Rams at the Melbourne Cricket Ground in Australia.

George Kittle and Nick Bosa Set for 49ers Return in NFL Season Opener

The San Francisco 49ers have received a significant boost ahead of their highly anticipated NFL Week 1 showdown against the Los Angeles Rams, with both tight end George Kittle and defensive end Nick Bosa cleared to return to the field. The two key starters are expected to suit up for the Thursday Night Football clash, which is being held at the Melbourne Cricket Ground in Australia.

Kittle’s return marks a notable recovery following a torn Achilles tendon sustained during the team’s wild-card playoff victory against the Philadelphia Eagles on January 11, 2026. Although the tight end was limited during practice sessions earlier this week, he has been removed from the official injury report and carries no game designation, confirming his availability for the season opener. NFL insider Adam Schefter confirmed the status of the veteran playmaker, noting his scheduled return to action in the international contest.

Defensive Reinforcements and Matchup Details

Defensive end Nick Bosa is also set to make his return after being sidelined since Week 3 of the 2025 season with a torn ACL. While the 49ers coaching staff, including defensive coordinator Raheem Morris, managed Bosa’s workload throughout the week with limited practice participation, he has been cleared to play. His presence is expected to bolster a San Francisco defense facing a Rams squad featuring notable contributors such as quarterback Matthew Stafford and recent acquisition Myles Garrett.